SiSiB® PC9210

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Technical Data

CAS No. 999 97 3

EINECS No. 213-668-5

Formula C6H19NSi2

Molecular Weight 161.4

Boiling Point 125°C

Flash Point 15°C

Ignition point 325°C

Color and Appearance Clear colorless liquid

Density 25/25°C 0.770

Refractive Index 1.407

Min.Purity 99.0%

Application

SiSiB® PC9210 hmds hexamethyldisilazane silylating agent can be used to introduce trimethylsilyl group into organic molecules containing an active hydrogen atom such as s, carboxylic acids, amines etc. The most common industrial SiSiB® PC9210 hexamethyldisilazane applications is in production of semi synthetic beta lactum antibiotics as ampicillin and cephalexin.

The usual procedure is to protect the carboxylic group in the antibiotic with HDMS followed by acylation with the desired acylchloride. Finally, desilylation under mild aqueous conditions gives the desired product.

Packing and Storage

SiSiB® PC9210 is supplied in 150Kg steel drum.

In the unopened original container SiSiB® PC9210 has a shelf life of one year in a dry and cool place.

For more information about hexamethyldisilazane uses, please feel free to contact us!