(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinolin
Quantité : 1kg; 25kg;
(S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline can be used to prepare solifenacin. Solifenacin succinate, CAS No. 242478-38-2, chemical name 1-azabicyclo[2.2.2]octan-8-yl-(1S)-1-phenyl-3,4-dihydro-1H-isoquinolin e-2-carboxylate succinate, is prepared by condensing (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline (I) with triphosgene under organic base (weak base) conditions to obtain (S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carbonyl chloride (II). Compound II can be directly heated in the presence of an organic base without separation through a one-pot method, and condensed with (R)-3-quinuclidine to obtain solifenacin (III), which is then salified with succinic acid to obtain solifenacin succinate (IV).
Brand: Soarwin
CAS No.: 118864-75-8
EC Number: 1806241-263-5
Molecular Formula: C15H15N
Density: 1.065
Melting point: 80-82°C
Boiling point: 338°C
Flash point: 167°C
Personne à contacter : Shelley Zhou, +17 7 23 84 28 51
Bonne affaire : acheter au vendeur
Nous vous invitons à lire nos conditions générales d'utilisations. Vous pouvez aussi vous rendre sur nos FAQ et consulter notre page d'informations sur les risques liés à la contrefaçon.
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Cette page concerne les importateurs et exportateurs de (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinolin Rechercher dans la catégorie : Matières premières Rechercher dans la catégorie : tetrahydroisoquinolin, phenyl |
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