CA242 Tumor Marker

CA242 tumor marker is almost always expressed together with CA50, but different monoclonal antibodies recognize the two. Clinically, the CA242 tumor marker has been used in the diagnosis of gastrointestinal malignancies, especially pancreatic and colorectal cancers.

Compared with CA19-9 tumour marker and CA50, the new generation CA242 tumor marker has higher sensitivity and specificity in pancreatic, gallbladder, and gastrointestinal cancers.

CA242 Tumor Marker Intro

Cancer antigen 242, a sialylated glycosphingolipid antigen, is a pancreatic and colon cancer marker. The increase is seen in 68% ~ 79% of pancreatic cancer, 55% ~ 85% of colon cancer, 44% of gastric cancer, and 5% ~ 33% of non-malignant tumors. Also, the positive rates of ovarian, uterine, and lung cancer were higher than CA50.

CA242 Blood Test

Cancer antigen 242 is a marker for the digestive system, especially colon, rectal and pancreatic cancer. It is superior to CA19-9 in diagnosing pancreatic cancer, with a sensitivity of 66% to 100%. It is also helpful for diagnosing liver cancer, gastric cancer, and esophageal cancer. However, ca242 blood test is not suitable for diagnosing squamous cell carcinoma.

Reference value: -12 units/ml (u/ml) (IRMA method).

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